What Side Effects Can Memodyne Cause? A Look at Each Ingredient
Quick answer
No study has tried this exact capsule, and the label lists no side effects. The sources describe stomach upset for the amino acids, mostly at gram doses. Tingling and flushing are unlikely at 40 mg beta alanine and 7.5 mg niacin. The bigger risk is low blood pressure with certain medicines. Ask a doctor first.
When people search for side effects, they usually want a short list. The honest answer starts with a gap: nobody has tested this capsule as a product. What exists are studies and drug references for each ingredient on its own, at amounts much larger than one capsule holds.
So this page does the careful thing. It takes the five ingredient groups one at a time, shows the effect each source lists and the amount researchers used, and then puts the capsule's own amount beside it. It ends with the signs that mean stop.
Key facts
- The label has a caution box but lists no side effects. What we know comes from research on each ingredient alone.
- Arginine forms: under 400 mg per capsule. Studies used grams. Mayo Clinic lists nausea, belly pain, bloating, diarrhea, headache and allergic reactions.
- Citrulline forms: under 200 mg per capsule. Trials used 3 to 9 g a day. The kidneys turn most of it into arginine.
- Beta alanine: 40 mg. Tingling is common from about 800 mg taken at once.
- Niacin: 7.5 mg NE. Flushing usually starts at 30 to 50 mg of nicotinic acid. The label does not name its niacin form.
- Calcium: 18 mg. Calcium carbonate can slow levothyroxine absorption within 4 hours.
- Small amounts make dose-driven effects less likely. They do not switch off drug interactions, because no source names a safe floor.
Does Memodyne have side effects?
It can, although no one has measured them for this capsule. The brand's own FAQ says no significant side effects have been reported. That is a statement from the seller, not a result from a study, and we treat it as marketing.
The useful way to think about risk is in two groups. The first is dose-driven effects such as loose stools or tingling. Small amounts make those less likely. The second is drug interactions. Those depend on what else you take, not on how small the capsule is.
What can each Memodyne ingredient do on its own?
| Ingredient | Effects the sources list | Studied at | In one capsule |
|---|---|---|---|
| L-arginine | Nausea, belly pain, bloating, diarrhea, gout, headache, allergic reactions, worse asthma; 9 to 30 g a day brought diarrhea and nausea in exercise research | 2 to 24 g a day | 200 mg base plus 200 mg AKG |
| L-citrulline | No side effects of its own in WebMD; 6 of 41 weightlifters in one study had stomach discomfort | 3 to 9 g a day | 100 mg HCl plus 100 mg malate |
| Beta alanine | Prickling skin on the face, neck and hands for 60 to 90 minutes, plus itch, at high doses | 1.6 to 6.4 g a day | 40 mg |
| Niacin | Red, hot, itchy skin from nicotinic acid at 30 to 50 mg or more | Adult need 14 to 16 mg NE; upper limit 35 mg | 7.5 mg NE |
| Calcium | Gas, bloating and constipation with calcium supplements | Adult need 1,000 to 1,200 mg | 18 mg as calcium carbonate |
Sources: (Mayo Clinic, L-arginine) (NIH ODS, Dietary Supplements for Exercise and Athletic Performance (health professional)) (WebMD, L-citrulline: Uses and Risks) (NIH ODS, Niacin (health professional)) (ISSN position stand: Beta-Alanine (2015)).
Will Memodyne cause beta alanine tingling or a niacin flush?
Both are unlikely at the label amounts. The pins-and-needles feeling is called paresthesia. It is common above about 800 mg taken at once (ISSN position stand: Beta-Alanine (2015)). One capsule holds 40 mg, a twentieth of that. WebMD describes the feeling as harmless and says it goes away by itself (WebMD, Beta-Alanine).
Flushing typically begins at 30 to 50 mg of nicotinic acid, and the adult upper limit from supplements is 35 mg (NIH ODS, Niacin (consumer)). One capsule gives 7.5 mg NE. If you also take a multivitamin or a pre-workout, add up the niacin on each label. The label does not say which niacin form Memodyne uses.
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Can arginine and citrulline lower blood pressure too far?
They can, and this is the main caution. Mayo Clinic notes that oral L-arginine has lowered blood pressure even in healthy people, and that pairing it with blood pressure drugs may push pressure too low (Mayo Clinic, L-arginine). RxList rates the interaction Major (RxList, L-Arginine (supplement monograph)).
Citrulline sits in the same conversation, because the body converts it into arginine. WebMD advises care with blood pressure medicine and says to avoid nitrates. With sildenafil, tadalafil or vardenafil it warns of a dangerous drop in blood pressure (WebMD, L-citrulline: Uses and Risks).
Which other medicines and conditions need a doctor's word?
| Medicine or condition | Ingredient | What the sources say |
|---|---|---|
| Diabetes medicines | Arginine | May lower blood sugar further, per Mayo Clinic and RxList |
| Blood thinners | Arginine | A possible rise in bleeding risk, per Mayo Clinic |
| Recent heart attack | Arginine | A trial gave about 9 g a day to 153 patients; six on arginine died and none on placebo |
| Frequent cold sores or herpes | Arginine | One source says it might make herpes worse |
| Levothyroxine | Calcium carbonate | Less medicine absorbed within 4 hours |
| Pregnancy, nursing, under 18 | Whole capsule | The label says to consult a physician |
The heart attack trial used about 9 g a day, which is over 20 times the arginine in one capsule. It does not prove harm at 400 mg. It explains why heart history matters (JAMA 2006, Schulman et al., L-arginine after heart attack (VINTAGE MI)).
When should you stop taking Memodyne and get help?
Stop and get help the same day for a serious reaction. Keep the bottle to show what you took.
- Swollen face or throat, hives or trouble breathing: call 911.
- Fainting, or dizziness each time you stand up.
- Stomach pain or diarrhea lasting more than a few days.
- A cold sore or herpes flare after you start.
- A broken or missing safety seal on arrival. Do not use that bottle.
The FDA asks people to stop and report a supplement that causes a problem (FDA, FDA 101: Dietary Supplements). Stopping does not cancel a refund request, but the 60-day window keeps running, so contact the order desk early at +1 (302) 200-3480.
Frequently asked questions
Does Memodyne have side effects?
It can. Stomach upset and headache are listed for arginine. The bigger risk is low blood pressure with heart, blood pressure or ED medicines.
Can I take Memodyne with blood pressure medicine?
Only after your doctor agrees. RxList rates arginine with blood pressure medicines as a Major interaction.
Will the beta alanine make me tingle?
Unlikely. Tingling is common from about 800 mg of beta alanine, and the capsule has 40 mg.
Will the niacin make my skin flush?
Unlikely at 7.5 mg NE. Flushing usually starts at 30 to 50 mg of nicotinic acid. The niacin form is not stated on the label.
Can arginine trigger cold sores?
Possibly. One drug-information source cautions that it might make herpes worse. If you get frequent outbreaks, ask a clinician first.
I felt dizzy after starting Memodyne. What should I do?
Stop taking it, sit down until it passes and call your doctor. Dizziness can mean your blood pressure fell.
Our view
Our view: for a healthy adult on no medicines, the capsule's own amounts are small, and the dose-driven side effects in the research are unlikely at those amounts. We say unlikely, not impossible, because no one has tested it.
The part that does not shrink with the dose is the interaction list. If you take blood pressure, nitrate, diabetes or blood thinning medicine, or you have had a heart attack, the right first step is a doctor or pharmacist with the label in hand. Memory that is getting worse also needs a doctor, not a supplement.
Last updated October 29, 2026. Medically reviewed by Dr. Harald Hampel, MD, PhD, MD, Physician, October 16, 2026.
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Page check
Written by
Compares each label amount with the doses used in published research, using NIH, FDA and Alzheimer's Association pages.
Medically reviewed by
Dr. Harald Hampel, MD, PhD, MD, Physician
Medical reviewer. Review date: October 16, 2026.
- Last compared with the label: October 16, 2026
- Facts come from the Supplement Facts panel and the brand pages; health lines come from the sources linked above
- Corrections go to [email protected]; our checking rules are on the standards page